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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CKM
All Species:
38.18
Human Site:
Y173
Identified Species:
60
UniProt:
P06732
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P06732
NP_001815.2
381
43101
Y173
T
G
E
F
K
G
K
Y
Y
P
L
K
S
M
T
Chimpanzee
Pan troglodytes
XP_001163660
381
42901
H173
C
G
E
I
G
V
P
H
C
S
H
R
S
M
T
Rhesus Macaque
Macaca mulatta
XP_001112108
381
42634
Y173
D
G
D
L
A
G
R
Y
Y
A
L
K
S
M
T
Dog
Lupus familis
XP_533641
488
54723
Y280
T
G
E
F
K
G
K
Y
Y
P
L
K
S
M
T
Cat
Felis silvestris
Mouse
Mus musculus
P07310
381
43026
Y173
T
G
E
F
K
G
K
Y
Y
P
L
K
S
M
T
Rat
Rattus norvegicus
P07335
381
42707
Y173
D
G
D
L
S
G
R
Y
Y
A
L
K
S
M
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508143
326
36755
N165
D
G
R
G
I
W
H
N
D
N
K
T
F
L
V
Chicken
Gallus gallus
P00565
381
43310
Y173
E
G
E
F
K
G
R
Y
Y
P
L
K
A
M
T
Frog
Xenopus laevis
NP_001080073
381
42887
Y173
S
G
E
F
K
G
K
Y
Y
P
L
K
D
M
S
Zebra Danio
Brachydanio rerio
NP_571007
381
42806
Y173
D
G
E
F
K
G
K
Y
Y
P
L
K
S
M
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48610
356
39848
T171
K
G
K
F
Y
P
L
T
G
M
E
K
A
V
Q
Honey Bee
Apis mellifera
O61367
355
39990
G171
G
T
F
Y
P
L
T
G
M
S
K
E
T
Q
Q
Nematode Worm
Caenorhab. elegans
Q27535
360
40364
T175
K
G
T
Y
Y
P
L
T
G
M
D
E
E
T
K
Sea Urchin
Strong. purpuratus
P18294
1174
130851
Y587
D
G
D
L
Q
G
K
Y
Y
P
L
E
G
M
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001169054
381
42707
Y173
D
G
D
L
S
G
R
Y
Y
A
L
K
S
M
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.3
80.5
75.1
N.A.
96.5
79.5
N.A.
70.3
90.2
88.7
88.7
N.A.
42.5
40.4
37.5
22.4
Protein Similarity:
100
97.3
90.2
77.4
N.A.
98.9
89.5
N.A.
78.2
95.8
95.5
94.2
N.A.
58.7
59
55.3
27.8
P-Site Identity:
100
33.3
60
100
N.A.
100
60
N.A.
6.6
80
80
93.3
N.A.
20
0
6.6
53.3
P-Site Similarity:
100
46.6
73.3
100
N.A.
100
73.3
N.A.
13.3
93.3
93.3
93.3
N.A.
40
20
20
80
Percent
Protein Identity:
N.A.
79.5
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
89.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
60
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
0
0
0
20
0
0
14
0
0
% A
% Cys:
7
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
40
0
27
0
0
0
0
0
7
0
7
0
7
0
0
% D
% Glu:
7
0
47
0
0
0
0
0
0
0
7
20
7
0
0
% E
% Phe:
0
0
7
47
0
0
0
0
0
0
0
0
7
0
0
% F
% Gly:
7
94
0
7
7
67
0
7
14
0
0
0
7
0
0
% G
% His:
0
0
0
0
0
0
7
7
0
0
7
0
0
0
0
% H
% Ile:
0
0
0
7
7
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
14
0
7
0
40
0
40
0
0
0
14
67
0
0
7
% K
% Leu:
0
0
0
27
0
7
14
0
0
0
67
0
0
7
0
% L
% Met:
0
0
0
0
0
0
0
0
7
14
0
0
0
74
0
% M
% Asn:
0
0
0
0
0
0
0
7
0
7
0
0
0
0
0
% N
% Pro:
0
0
0
0
7
14
7
0
0
47
0
0
0
0
0
% P
% Gln:
0
0
0
0
7
0
0
0
0
0
0
0
0
7
14
% Q
% Arg:
0
0
7
0
0
0
27
0
0
0
0
7
0
0
0
% R
% Ser:
7
0
0
0
14
0
0
0
0
14
0
0
54
0
14
% S
% Thr:
20
7
7
0
0
0
7
14
0
0
0
7
7
7
60
% T
% Val:
0
0
0
0
0
7
0
0
0
0
0
0
0
7
7
% V
% Trp:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
14
14
0
0
67
67
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _